Indicators are weak acids or bases that exhibit extreme hues that vary with pH. The conjugate acid and conjugate base of an excellent indicator have pretty different hues in order that they may be distinguished conveniently. Some indicators are colorless while in the conjugate acid kind but intensely coloured when deprotonated (phenolphthalein, as
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Administration to Wistar rats for 2 yrs of 2 g/kg bw on a daily basis sodium saccharin while in the drinking-water or of 4 g/kg bw each day in the diet lessened the burden gain markedly; fluid intake was enhanced from the latter team and lowered in the previous. The normal urinary pH of males in the very first group had risen to over 7.0 by 27 week
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